Current Issue

Year 2019

Volume: 5 , Issue: 2

Print ISSN:-2581-4796

Online ISSN:-2581-480X

Member of


IP Annals of Prosthodontics and Restorative Dentistry


Bisphophonates and dental Implants – A literature review


Full Text PDF Share on Facebook Share on Twitter


Author Details: Rahul Sharma, Dhruv Anand, Ashish Choudhary, Jay Vikram, Anurag Hasti

Volume : 3

Issue : 2

Online ISSN : 2581-480X

Print ISSN : 2581-4796

Article First Page : 60

Article End Page : 62


Abstract

Osteonecrosis of the jaw has been described in patients taking bisphosphonates after oral surgery procedures, including the placement of dental implants. The success of these procedures depend on the fixation of the implants which, in turn depends on the strength of the bone that holds them. Bisphosphonates are anti-resorptive drugs that act specifically on osteoclasts, thereby maintaining bone density and strength. These drugs inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer. At present, there is no effective treatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Since quality of life deteriorates for those suffering osteonecrosis, maximum precautions should be taken with patients at risk. The aim of this study was to conduct a systematic review in order to evaluate whether patients on BP therapy are appropriate candidates for dental implants as compared to patients not taking BP drugs with respect to successful implant osseointegration and the risk of developing bisphosphonaterelated osteonecrosis of the jaw.

Keywords:
Bisphosphonates, Osteonecrosis of the jaw, Osseointegration, Dental implants