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Indian Journal of Clinical Anaesthesia

ā€œAttenuation of haemodynamic changes during laryngoscopy and endotracheal intubation using IV lidocaine versus IV cloridineā€

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Author Details: Rama Krishna Reddy Mudiganti, Rishita Reddy Magam, Rambabu T

Volume : 3

Issue : 2

Online ISSN : 2394-4994

Print ISSN : 2394-4781

Article First Page : 224

Article End Page : 232


Background: Haemodynamic changes such as hypertension and tachycardia due to laryngoscopy and endotracheal intubation are well known, which are not tolerated by some patients with history of Hypertension, CAD. To attenuate these responses many drugs have been tried.
Aim: To compare the efficacy of IV cloridine in attenuating of haemodynamic responses during laryngoscopy & endotracheal intubation in comparison with IV plain lidocaine.
Design: Randomised controlled study.
Material & Method: The study includes 100 patients, randomly divided into 2 groups. Group L (50 patients) were given IV Lignocaine and Group C (50 patients) IV Cloridine was given.
Statistical Analysis: Descriptive statistics and independent & paired sample ‘t’ tests.
Results & Conclusion: Cloridine in the dose of 3μg/kg IV, given 15 minutes before laryngoscopy and intubation can be a better alternative than IV lidocaine 1.5mg/kg 3 minutes before laryngoscopy and intubation, in attenuating the haemodynamic responses to laryngoscopy and intubation without any side effects. In addition Cloridine also has other advantages such as decrease in the requirement of inhalational agents, desirable sedation etc.

IV lidocaine versus IV Cloridine Haemodynamic changes, Layngoscopy, Intubation, Cloridine Lidocaine