Current Issue

Year 2019

Volume: 6 , Issue: 3

Print ISSN:-2394-4781

Online ISSN:-2394-4994

Member of

Indian Journal of Clinical Anaesthesia

Comparison of epidural ropivacaine vs bupivacaine with addition of fentanyl or dexmedetomidine in major lower limb orthopaedic surgery

Full Text PDF Share on Facebook Share on Twitter

Author Details: Ajay Sriram Ayyappan, Kannan Santhanakrishnan

Volume : 4

Issue : 1

Online ISSN : 2394-4994

Print ISSN : 2394-4781

Article First Page : 56

Article End Page : 63


Background: Adequate analgesia following major lower limb orthopaedic surgeries is necessary for both intra and post-operative pain relief, to promote early ambulation and improved patient outcome.
Aim: To study and compare the analgesia and patient satisfaction when using the local anesthetic drugs ropivacaine and bupivacaine with the adjuvants, fentanyl or dexmedetomidine in major lower limb orthopaedic surgeries.
Materials and Methods: 80 patients undergoing major lower limborthopaedic surgeries under combined spinal epidural anaesthesia were randomly divided into 4 groups. Group RF received Ropivacaine 0.2% with Fentanyl 2µg/ml, Group RD received Ropivacaine 0.2% with Dexmedetomidine 2µg/ml, Group BF received Bupivacaine 0.125% with Fentanyl 2µg/ml and Group BD received Bupivacaine 0.125% with Dexmedetomidine 2µg/ml as epidural infusion. Effective analgesia, sensory level, motor block, patient satisfaction were measured. The statistical analysis was done using ANOVA, student ‘t’ test, Mann- whitney test and chi square test. P value < 0.05 was taken as statistically significant.
Results: Group Bupivacaine with dexmedetomidine had a very high patient satisfaction and analgesia when compared to the other groups.
Conclusion: Addition of epidural Bupivacaine with dexmedetomidine as an adjuvant provides slightly better analgesia and patient satisfaction when compared to ropivacaine with dexmedetomidine or fentanyl in patients undergoing major lower limb orthopaedic surgeries.

Bupivacaine, Ropivacaine, Dexmedetomidine, Fentanyl