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Indian Journal of Clinical Anaesthesia


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Author Details: Ravi Kumar, Sreedevi K. P

Volume : 2

Issue : 2

Online ISSN : 2394-4994

Print ISSN : 2394-4781

Article First Page : 102

Article End Page : 106


Background: This study was designed to evaluate the efficacy, onset and duration of sensory and motor blockade, occurrence of delirium reaction and other complications of Ketamine with Adrenaline given intrathecally.

Methods: 100 patients belonging to ASA grade-I & II of both sexes scheduled for lower abdominal surgery were randomly selected for the study. 7All the patients received injection Ketamine 75mg with Adrenaline 100 microgram intrathecally. The onset of sensory and motor blockade, maximum level and time taken for sensory level, quality and duration of sensory and motor blockade, intra-operative complications were assessed.
Results: The onset of sensory and motor blockade was in 2.60±0.64 minutes, 4.33±0.60 minutes respectively. The duration of sensory and motor blockade was 85.48±11.68 minutes, 108.36±11.78 minutes respectively. The maximum level achieved ranged from T6-T10. The time taken to achieve maximum sensory blockade ranged from 2-8 minutes. There were no significant changes in mean systolic and diastolic arterial blood pressure or pulse rate. Intra-operatively, nystagmus was seen in all patients. Sedation and delirium was seen in 70 patients and 4 patients respectively.
Conclusion: Ketamine with adrenaline produced a quicker onset of sensory blockade with good muscle relaxation. Ketamine stimulated the cardiovascular and respiratory systems, which may be an advantageous in maintaining stable haemodynamics over local anaesthetics during perioperative period for lower abdominal surgeries.
Keywords: Ketamine; Adrenaline; Intrathecal; Anaesthesia