IP International Journal of Comprehensive and Advanced Pharmacology


Study of clinical outcomes of patients suffering from acute Myocardial Infarction in Pravara Rural Hospital, Loni


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Article Type : Review Article

Author Details: Jaini Shah,Sandeep P. Narwane*

Volume : 4

Issue : 1

Online ISSN : 2456-9542

Print ISSN : 2581-5555

Article First Page : 21

Article End Page : 25


Abstract

Introduction: The aim of present study was to study the immediate outcome of fibrinolytic therapy, to correlate the time of institution of fibrinolytic therapy with clinical outcomes in patients suffering from Acute Myocardial Infarction in Pravara Rural Hospital, Loni. Material and methods: It was a retrospective study carried out in collaboration with the Department of Medicine, Pravara Rural Hospital, Loni. All complete records of the patients diagnosed with AMI of age 18 & above of both gender and who received fibrinolytic therapy were included in the study. Records of patients with reinfarction, history of renal disorders, congenital cardiac defects, cardiomegaly, and peripheral vascular diseases were excluded. The age, gender, co-morbidities, history of addiction, time to institution of fibrinolytic therapy, immediate clinical outcome, ECG changes was collected from the records.
Results: 150 patient’s records were included for the study, of which 122(81.3%) were males and 28(18.6) were females. The average age of patients was 56.95±12 years. The common comorbidities seen in the present study were Diabetes mellitus and Hypertension. Addiction of tobacco chewing, smoking and Alcohol consumption was observed in 67.3% of patients. STEMI was observed in 73.3% of patients, while NSTEMI and other ECG abnormalities were observed in 26.6% of patients. Only 21(14%) patients reported within one hour of complaints, 63 (42%) patients reported after between 1 and 6 hours, while 51(34%) patients reported after 6 hours. There was no correlation found in the time of institution of fibrinolytic therapy and clinical outcome of the patients.
Conclusion: Delay in hospitalization of patient of AMI is common. There is a rising trend of AMI seen in the younger age group leading to pre mature death and mortality. AMI was commonly observed in males of middle age group, addiction of tobacco, history of hypertension and diabetes and ECG changes of ST segment elevation. There was no correlation found between the time of institution of fibrinolytic therapy and immediate clinical outcome of the patients. Further studies are required to establish the reasons behind delay in hospitalization of patients.

Keywords: Acute Myocardial Infarction, Thrombolytics, Fibrinolytic, Acute coronary syndrome.

Doi :-https://doi.org/10.18231/j.ijcaap.2019.005