• Indexing List

International Journal of Clinical Biochemistry and Research

Study of Serum Cystatin C, Lipid Profile and Electrolytes in Acute Stroke Patients

Full Text PDF Share on Facebook Share on Twitter

Author Details: Arindam Sur, Pramila Kumari Mishra, Manorama Swain, Namita Mohapatra

Volume : 2

Issue : 4

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 194

Article End Page : 197


Background: The effectiveness of cystatin C as a biomarker in acute hemorrhagic/ischemic stroke is being studied recently. It is due to accumulating evidence indicating a link between vascular disease of the kidney and brain. In this study we have investigated the association of serum cystatin C with first onset acute stroke.
Methods: A total of 45 patients with first onset stroke, aged more than 30 years, were selected for the study based on history, detailed clinical examinations, neuro-imaging and other related investigations. The patients were presenting within 72 hours after onset of symptoms.
Results: Serum cystatin C levels were significantly elevated (p<0.0001) in cases (1.60±0.88 mg/l) when compared with controls (0.82±0.11 mg/l). Serum creatinine levels were also significantly elevated (p<0.001) in cases (1.77±1.23 mg/dl) when compared with controls (1.05±0.18 mg/dl). Among lipid profile parameters, total cholesterol, triglycerides, LDL and VLDL cholesterol were all significantly increased in cases when compared with controls. Key words: Acute stroke, Cystatin C, Dyslipidemia, Electrolytes.