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International Journal of Clinical Biochemistry and Research

A case control study of stress and infertility in hypothyroid reproductive age group women residing in Udaipur, Rajasthan, India

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Author Details: Neha Sharma, Pooja Gandhi, K.L. Mali, Arjun Lal Jain

Volume : 3

Issue :

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 89

Article End Page : 99


Introduction: Challenges to human being fertility may occur from numerous condi­tions caused through hereditary abnormalities, communicable or else environ­mental agents, as well as certain behaviors. Reproduction is one of the essential functions for every life form. The age of male or female is a reason along with others to be able to have an effect on fertility. Owing to chase of education as well as supplementary factors, lots of couple is choose to wait for childbearing.
Methods: This study was done on hypothyroid reproductive age group women at Geetanjali Medical College and Hospital, Udaipur, Rajasthan after obtaining GMCH ethical committee approval. Serum TSH, FSH LH, PRL was performed on automated system cobas e-411 (CLIA) and IL-6 was done by ELISA method.
Results and conclusions:   Significant changes were occurred in serum FSH, LH and PRL along with IL-6 in 20-36 years of age group of subjects and changes in menstrual pattern along with the stress. Positive correlation between IL-6 and TSH was found in hypothyroid reproductive age group women, individuals who were childless.

Key words:
Hypothyroid, Infertility, Oligomenorrhoea, Prolactin, Thyroid hormone