International Journal of Clinical Biochemistry and Research


Prevalence of High Lipid Profile in Diabetes Meellitus Patients: A Study in a Tertiary Care Centre


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Author Details: N.Jaya, Nasika Chowdeswari

Volume : 3

Issue : 1

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 120

Article End Page : 123


Abstract

Introduction: Diabetes mellitus is a group of metabolic diseases characterized by increased blood glucose levels resulting from defects in insulin secretion, insulin action, or both. It is also associated with interrelated plasma lipid and lipoprotein abnormalities, including reduced HDL cholesterol, elevated triglyceride and LDL levels. Each of these dyslipidemic features is associated with increased cardiovascular risk and as a result, mortality.
Materials and Methods: 476 patients between 18 – 80 years were selected randomly and included into the study. The patients were divided into 2 groups, one with blood sugar levels below 110mg/dl and the other within normal limits. Biochemical tests such as fasting blood sugar, post parandial blood sugar, lipid profile including triglyceride levels, HDL cholesterol, LDL cholesterol and total cholesterol were done for all the patients.
Results: Out of 476 patients, 249 were diabetic with fasting blood sugar above 110mg/dl and 227 patients had FBS levels within the normal limits. Out of the diabetic patients, 51% were males and 49% were females. In the controls group, there were 52.4% males and 47.6% females.
Conclusion: There is a high prevalence of high degree of elevated lipid and lipoprotein levels among the diabetic patients showing that they are more prone to these abnormalities.

Keywords:
Diabetes mellitus, lipid levels, lipoproteins, cholesterol, triglycerides