International Journal of Clinical Biochemistry and Research


Significance of hs-CRP in vestibular dysfunction in type II diabetes mellitus


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Author Details: Sumathi K, Prakash M, Parameaswari PJ, Mary Chandrika A

Volume : 3

Issue : 4

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 392

Article End Page : 394


Abstract

Background: The most common morbid complication of Type-2 diabetes mellitus is vestibulopathy. Microangiopathy & Oxidative stress due to diabetes mellitus is one of the causative factor of this vestibular dysfunction.
Aim and Objectives:  The aim of the study is to find the significance of hs-CRP in vestibular dysfunction in type 2 diabetes mellitus.
Materials and Methods: A cross-sectional study of 100 diabetic patients were tested for vestibular function by electronystagmography. Clausen butterfly chart is generated based on the bithermal caloric stimulation and the code is ascertained & Serum hsCRP was estimated for these patients by immunoturbidometry. Data analysis done using SPSS package.
Results: 65% of diabetic population with hsCRP>3mg/L had vestibular dysfunction which is significant.  It is also found that 70% of diabetic patients with greater than 4 years duration had vestibular dysfunction.
Conclusion: From this study it is concluded that the proportion of diabetic vestibulopathy is higher in those having hsCRP of >3mg/L. So it is advisable to do screening for all diabetics by estimating hsCRP & vestibular dysfunction particularly those having hsCRP >3mg/L so as to prevent the morbid complication diabetic vestibulopathy.

Keywords:
Diabetic Vestibulopathy, Electronystagmography, hsCRP, Clausen butterfly chart.