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International Journal of Clinical Biochemistry and Research


Evaluation of hsCRP, Insulin and Insulin resistance in Polycystic Ovarian Syndrome


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Author Details: Sapna Jangir, Jairam Rawtani

Volume : 4

Issue : 2

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 195

Article End Page : 197


Abstract

Introduction: Polycystic Ovarian Syndrome consists of a constellation of metabolic abnormalities and is now well recognised having a major effect throughout life on the reproductive, metabolic and cardiovascular health of affected women.
Objective: The present study was conducted to evaluate hsCRP, insulin and insulin resistance levels in PCOS patients.
Materials and Method: 30 PCOS subjects in the age group of 18 to 34 years and 25 age-matched healthy women as controls were evaluated.
Result: Serum hsCRP, insulin, insulin resistance, BMI and waist-to-hip ratio were significantly elevated (p<0.0001) in PCOS cases when compared with controls. There was a positive correlation between hsCRP and insulin (p=0.2001) and hsCRP and insulin resistance (p = 0.127) in PCOS patients.
Conclusion: PCOS women have added risk of complications of cardiovascular disease and Diabetes mellitus.

Keywords:
Cardiovascular disease, Diabetes mellitus, hsCRP, Insulin resistance, Polycystic Ovarian Syndrome, Inflammation