International Journal of Clinical Biochemistry and Research


Study of iodine nutrition level in pregnant south Indian subjects in third trimester


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Author Details: Suresh Pichandi, Desigamani Kanniyappan, Janakiraman P, Ramadevi K

Volume : 5

Issue : 1

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 143

Article End Page : 147


Abstract

Objective: Aim of the present study is to analyse the nutritional status of iodine among pregnant women by measuring urinary excretion and do the correlation with thyroid hormone and auto antibodies.
Materials and Methods: one hundred pregnant women with third trimester gestation and one hundred age-matched non-pregnant were included in study.
Results: Urinary Iodine excretion and serum TSH, fT4, fT3, AMA and ATG were estimated were estimated for case and control groups. The mean urinary iodine excretion concentration (UIC) in pregnant women was 290.17±91.71 µg/L. Excess urinary iodine excretion was found in 69%. There were elevated serum AMA levels in 36 pregnant women and that positive correlated with excess iodine.
Conclusion: The pregnant women had no iodine deficiency, rather had high urinary iodine concentrations indicating more than adequate iodine intake. The excess urinary iodine level may tiger the thyroid auto antibody.

Keywords: Urinary iodine excretion (UIE), thyroid stimulating hormone (TSH), free thyroxine (fT4), free tri-iodothyronine (fT3), anti-microsomal antibody (AMA), anti-thyroglobulin antibody (ATA), pregnancy, iodine excess.

Doi :-https://doi.org/10.18231/2394-6377.2018.0029