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International Journal of Clinical Biochemistry and Research

Assessment of mineral status in subclinical hypothyroidism patients – A case control study

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Author Details: Mamatha B.V*,Chandrakanth K.H,Kashinath R.T,Rakshitha M.N

Volume : 6

Issue : 1

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 32

Article End Page : 35


One of the important functions of thyroid hormones is homeostasis of mineral metabolism. So thyroid disorders usually lead to disturbances in mineral metabolism.
Objective: To analyze serum levels of minerals like calcium, phosphorus and magnesium in patients of subclinical hypothyroidism and to correlate these parameters with TSH levels in cases.
Materials and Methods: The study group included 70 patients who are diagnosed with subclinical hypothyroidism and 70 healthy controls who are age and sex matched with cases. Thyroid profile which includes estimation of serum T3, T4, TSH was done. Serum calcium, phosphorus and magnesium were also estimated in both cases and controls.
Results: The study showed that in subclinical hypothyroidism patients serum calcium levels were significantly low with mean values of 8.9±0.62 and p<0>
Conclusion: The serum levels of minerals like calcium, phosphorus and magnesium levels are significantly altered in subclinical hypothyroidism. Frequent follow up and checking the levels of these minerals in SCH patients should be done. Along with the treatment of the disease, it is necessary to give mineral supplements to prevent bone complications.

Keywords: Calcium, Phosphorus, Magnesium, Subclinical hypothyroidism, Thyroid stimulating hormone, Thyroid hormones.

Doi :-https://doi.org/10.18231/2394-6377.2019.0009