International Journal of Clinical Biochemistry and Research


Study of thyroid dysfunction in young adults coming to tertiary care hospital Kanpur


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Article Type : Research Article

Author Details: Pallavi Anand,Parul Gupta*

Volume : 6

Issue : 2

Online ISSN : 2394-6377

Print ISSN : 2394-6369

Article First Page : 222

Article End Page : 225


Abstract

Introduction: The aim of this study was to check and compare FT3, FT4 and TSH levels in young adults (age group 18 – 35) for thyroid dysfunction. To check the thyroid hormones level in young adults (age group 18 – 35) in control and hypothyroidism and to compare them. 
Materials and Methods: The study group included 200 subjects (young adults) taken from Rama Medical College and hospital, Kanpur. In which 100 were hypothyroidism and 100 were control. The thyroid profile (FT3, FT4 and TSH) was analysed in these individuals by Electrochemiluminescence technique. 
Result: When control group was compared with hypothyroidism group then significant increase in TSH level and significant decrease in FT3 and FT4 level was found in hypothyroidism group. When level was compared between male (n=31) and female (n=69) then significant increase of TSH level was found in female group. When level was compared between male (n=32) and female (n=68) group in hypothyroidism then significant increase in TSH level was found in female group. The FT3 and FT4 levels were non-significant between male and female within the groups in both control and hypothyroidism. The levels of (TSH, FT3 and FT4) were significant higher in male and female groups in hypothyroidism when compared to male and female groups in control. 
Conclusion: This study suggests that TSH level increases with age which is irrespective to gender difference. 

Keywords: Hypothyroidism, Free triiodothyroxine, Free thyroxine, Thyroid stimulating hormone.

Doi :-https://doi.org/10.18231/j.ijcbr.2019.049