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IP Indian Journal of Clinical and Experimental Dermatology

Evaluation of Efficacy and Safety of Modified Technique of Autowart Injection Therapy in the Treatment of Multiple, Recurrent and Recalcitrant Warts

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Author Details: Mukunda Ranga Swaroop, Periasamy Vasudevan

Volume : 1

Issue : 1

Online ISSN : 2581-4729

Print ISSN : 2581-4710

Article First Page : 1

Article End Page : 3


Background: Multiple recurrent warts affect patient’s quality of life by causing physical and psychological discomfort. Common treatment modalities are painful, cause scarring, have high recurrence rates and are impractical for treatment of multiple lesions. Immune stimulation by exposing the viral antigens to body’s immune system forms an ideal modality of treatment. Autowart injection works under this principle.
Aim: To evaluate the safety and efficacy of modified technique of auto wart injection in the treatment of multiple recurrent recalcitrant warts.
Methods: A total of 40 patients with multiple recurrent cutaneous warts were enrolled in this prospective open labelled study. The donor tissue was harvested by just paring the wart, instead of taking the whole of wart tissue. The harvested tissue was then crushed and injected in the gluteal region in suspension of 1 ml of distilled water. Patients were followed up once in 2 weeks for one month and then monthly for 3 months. Patients were evaluated with lesion count at each visit and the response to the treatment was assessed at the end of 12 weeks.
Results: All 40 patients with multiple warts (male: female = 29:11) were available for follow-up. At the end of 3 months, 28 patients (75%) showed complete clearance of warts, 9 patients (22.5%) had partial clearance and one patient showed no improvement. No apparent side effects were observed.
Conclusion: Modified autowart injection technique was found to be a safe and effective therapeutic modality with rapid resolution of warts in the treatment of multiple, recurrent, recalcitrant warts.

Key Words: Auto wart injection; Immune stimulation; Paring; Multiple, Recurrent, Recalcitrant warts