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Indian Journal of Clinical and Experimental Ophthalmology

Effect of 5% phenylephrine eye drops on blood pressure

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Author Details: Mohammed Ather, Rahmathunissa, Saudhamini Siguru, Wajhia Sultana

Volume : 3

Issue : 2

Online ISSN : 2395-1451

Print ISSN : 2395-1443

Article First Page : 189

Article End Page : 191


Aim: To study effect of 5%phenylephrine eye drops on Blood Pressure.
Materials and Methods: This is prospective randomly controlled study conducted at the department of Ophthalmology of Gandhi Hospital during January 2015 to December 2015. 50 patients between 30-70 years of age who came for eye check up to Gandhi Hospital were included in study. Informed consent was obtained from all patients. The patients who had Secondary Hypertension because of systemic disease like chronic renal failure, Pregnancy induced hypertension and other diseases were excluded from the study. Off 50 patients 25 had Primary Hypertension and came for eye check up with various complaints. 25 patients with matching age group of 30-70 years who were non Hypertensives were included as controls in the study. Blood pressure was recorded in all 50 patients as base line. Then one drop of 1% Tropicamide and 5% Phenylephrine eye drop combination was instilled into lower fornix of all patients after recording BP and every 15 minutes up to 30 minutes. The BP was recorded after 30 minutes again.
Results: Rise in both Systolic and Diastolic pressure was observed in Group 1 i.e.: Hypertensives. Whereas in group 2 non hypertensives only rise in Systolic pressure was observed.
Conclusion: 5% Phenylephrine causes rise in both systolic and diastolic pressures in Hypertensive group. The rise was20-40 mmHg in systolic and 10-20mmHg in diastolic pressure. The rise was significant in patients who were aged between 60-70 years irrespective of their sex. So it has to used with caution in elderly hypertensives.

Diastolic Pressure, Hypertensives, Phenylephrine, Systolic pressure