Indian Journal of Clinical and Experimental Ophthalmology

Outcome of penetrating keratoplasty in pseudophakic bullous keratopathy

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Article Type : Research Article

Author Details: Archana R. Thool*,Sweta Ambadkar

Volume : 5

Issue : 3

Online ISSN : 2395-1451

Print ISSN : 2395-1443

Article First Page : 282

Article End Page : 286


Introduction: To study the outcome of penetrating keratoplasty in pseudophakic bullous keratopathy  in terms of visual acuity, graft survival, complications and to identify prognostic factors.
Materials and Methods: This was a hospital based, prospective interventional study, which included 24 eyes of 24 patients with pseudophakic bullous keratopathy who underwent penetrating keratoplasty with interrupted sutures by single corneal surgeon. Eyes with posterior chamber IOL were retained, eyes with anterior chamber IOL were explanted without IOL exchange. Cases were followed upto 6 months. The outcome was assessed in terms of visual acuity, graft survival, complications and post keratoplasty astigmatism as depicted on corneal topography at the end of 6 months.
Results: Out of 24 cases, 5 cases were of regraft, 1 case was lost to follow up. Percentage of cases gaining visual acuity of 6/60 or more was 60.86%, clear grafts were 87%, graft failure was 13%. Incidence of post penetrating keratoplasty glaucoma was 30.43%. Astigmatism ranged from 6 to 13 dioptres as a difference between simulate keratometric value of steep meridian and flat meridian on corneal topography at 6 months.
Conclusion: Penetrating keratoplasty in pseudophakic bullous keratopathy has good short term graft survival and moderate visual recovery. Retained posterior chamber IOL helped in better visual outcome. Glaucoma and immunological rejection were main causes for graft failure. Quality of donor tissue improves the outcome of penetrating keratoplasty.

Keywords: Graft survival, Pseudophakic bullous keratopathy, Penetrating keratoplasty.

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