Indian Journal of Clinical and Experimental Ophthalmology


Analysis of efficacy of intraoperative mitomycin C in external dacryocystorhinostomy


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Article Type : Research Article

Author Details: Srinivasan Gopalan*,Kalpana Ramamoorthy,Bhavana Sharma

Volume : 5

Issue : 3

Online ISSN : 2395-1451

Print ISSN : 2395-1443

Article First Page : 339

Article End Page : 342


Abstract

Introduction: The success of dacryocystorhinostomy (DCR) depends upon the patency of the lacrimal passage following the procedure. Mitomycin C has a wide application in Ophthalmology. In this present study, conventional external DCR was compared with external DCR were intra operative Mitomycin C was used, in order to prevent fibrosis at the osteotomy site following the procedure.
Material and Methods: There were 40 patients in this study who were divided into 2 groups. In group A, MMC was used intraoperatively at the osteotomy site for a period of five minutes. In Group   B, Conventional External DCR was done without using an adjuvant. The study population included patients with acquired naso lacrimal duct obstruction .After the surgery, patients were assessed at 1st week, 1st, 3rd   and 6th month respectively.
Results: The mean age of the study group was 40.29+/-9.53 years. Patients in both the groups were followed up regularly.  Postoperatively at 6th month of visit, it was found that 1  (5%) out of 20 patients  in Group A (MMC) and 4 patients  (20%) among 20  in Group B(Conventional) reported with symptoms of watering of eyes and on examination had a high tear meniscus height, thereby had a non-patent lacrimal drainage system following surgery. On comparison there was a statistically significant difference between the two groups with the P value of 0.001. It was revealed that success rate was better in MMC group when compared with the Conventional group.

Keywords: Complications, Dacryocystorhinostomy, Mitomycin C.

Doi :-https://doi.org/10.18231/j.ijceo.2019.081