Indian Journal of Clinical and Experimental Ophthalmology

Study of visual outcome in patients undergoing penetrating keratoplasty

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Article Type : Research Article

Author Details: Vaishali*,Kavita Kumar,Bhavana Sharma

Volume : 5

Issue : 3

Online ISSN : 2395-1451

Print ISSN : 2395-1443

Article First Page : 352

Article End Page : 357


Introduction: To study the visual outcome in patients undergoing penetrating keratoplasty (PK).
Materials and Methods: This was a prospective interventional study concerning patients who underwent optical and therapeutic PK in Hamidia hospital Bhopal during a period of Dec 2016 to May 2108. Age, gender, eye, indication of PKP, and best-corrected visual acuity (BCVA) constituting the preoperative data were recorded in a predesigned proforma. Penetrating keratoplasty was performed using similar technique and patients were followed up till a period of 1 year and post operative complications were identified and managed accordingly. The outcome was assessed in terms of percentage improvement in logMAR visual acuity and the variables affecting the final visual outcome were studied.
Results: Of the total 50 cases of penetrating keratoplasty that were analyzed 33 were done for therapeutic purposes and 17 were done for optical reasons. Mean recipient age was 39.88 years ±2.9 years, range 3-68. Follow up period was 1 year. The indications were therapeutic (34%), post traumatic or post infective corneal scarring (50%), previous graft failure (6%) and pseudophakic bullous keratopathy (4%). In optical PK, 62.5% recipient eyes showed good visual improvement (improvement of more than -0.8 log MAR). 21.8% eyes showed moderate visual improvement, and 15.6% eyes showed no visual improvement. In eyes with therapeutic PK, 46.7% showed good visual improvement, 13.3% moderate and 40% showed no visual improvement.
Conclusion: Penetrating keratoplasty done for both optical and therapeutic indications resulted in fairly good visual outcome. The pre-operative host risk factors were associated with an increased probability of graft rejection. Careful workup of recipients for corneal transplantation with reference to local and systemic risk factors is of utmost importance in the outcome of corneal transplantation with regards to graft survival.

Keywords: Corneal vascularisation, Graft failure, Penetrating keratoplasty.

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