Indian Journal of Forensic and Community Medicine


Estimation of coronary artery calcium by multislice spiral CT scan in asymptomatic high risk cases above forty (40) years of age


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Author Details: Umesh Giradkar, Sandesh Chaudhari, Mandar Ramchandra Sane, Anand B. Mugadlimath, Naresh Kumar

Volume : 3

Issue : 3

Online ISSN : 2394-6776

Print ISSN : 2394-6768

Article First Page : 220

Article End Page : 224


Abstract

Hypertension, diabetes mellitus, smoking, obesity and family history of coronary artery disease are among known risk factors of coronary artery disease. Computed tomography (CT) quantifies the relative burden of CAC deposits as a marker of atherosclerosis.
Methodology: This was a case control study conducted at Indira Gandhi Medical College and Hospital, Nagpur from June 2004 to June 2006, with aim to find out the utility of multislice spiral computed tomographic (CT) scan for detection of coronary artery calcium in asymptomatic coronary high risk cases and attempts has been made to correlate CAC Score with various risk factors and has been compared with CAC Score of controls
Results: The maximum numbers of cases were in group of 41-50 years (n=31, 53.4%). The male to female ratio was 1.52:1. Among the risk factors studied, dyslipidemia (65.5%) was most common risk factor. Mean CAC score of all cases was significantly higher than, mean CAC score of all controls (p value= 0.0004). There was a progressive increase in the mean CAC score with increasing age. When all the risk factors were individually compared with controls, all showed higher CAC score and all the differences were statistically highly significant.
Conclusion: Coronary artery calcium increases with increasing age and male sex. It also increases with presence of major risk factors for coronary artery disease (CAD). Hence, multislice spiral CT scan, being a non-invasive test can be recommended as a screening test for demonstrating significant atherosclerosis in susceptible subjects even when asymptomatic.

Keywords:
Coronary artery diseases, Coronary artery calcium, Ct scan risk factors