IP Indian Journal of Immunology and Respiratory Medicine


To study different etiological and prognostic factors in patients suffering from ARDS/ALI


Full Text PDF Share on Facebook Share on Twitter


Article Type : Research Article

Author Details: Praveen Subhash Chabukswar*,Jaya Bhaskar Baviskar

Volume : 4

Issue : 2

Online ISSN : 2581-4222

Print ISSN : 2581-4214

Article First Page : 104

Article End Page : 108


Abstract

Background: Acute inflammatory reaction in the lung which causes injury to the endothelial cells and alveolar epithelium are main pathological changes that may occur in ARDS. This leads to pulmonary edema which eventually causes respiratory failure in these patients. Multiple organ dysfunction syndrome (MODS) is common consequence in these patients. Mortality rate corresponds to the severity of underlying disease and it ranges from 10% to 90%.
Methodology: All patients were screened for the diagnostic criteria of ARDS as per the 1994 American European Consensus Conference on ARDS/ALI. Different scores suggesting outcome were calculated on admission to intensive care unit. Objectives of study were [1] To identify the different risk factors responsible for ARDS/ALI, [2] To study the lung functions in ARDS/ALI survivors, [3] To analyze the effect of treatment strategies on lung functions in survivor, [4] To study different scoring systems.
Results: In our study we had a total of 65 patient, out of which 35 survived. The risk factors for developing ALI/ARDS were pneumonia, tropical diseases, postoperative sepsis, poly trauma, tuberculosis, malignancy, poisoning and neurological disorder.
Conclusions: Pneumonia and tropical diseases are the common risk factor for the ARDS/ALI. The presence of co-morbid conditions also affects the outcome of ALI/ARDS patients. MODS of >4, LIs >2 and APACHE II >2 had associated with higher mortality.

Keywords: ARDS; ALI; Pneumonia.

Doi :-https://doi.org/10.18231/j.ijirm.2019.024