Volume : 4
Issue : 2
Online ISSN : 2581-4761
Print ISSN : 2581-4753
Article First Page : 76
Article End Page : 79
Objective: To compare the prevalence of UTI in diabetic and non-diabetic patients and to compare its antibiotic resistance pattern.
Materials and Methods: A cross-sectional study was conducted in 228 diabetic and 228 non-diabetic patients from November 2016 to January 2018. After obtaining an informed consent, clinical data was collected using pre-structured questionarre. Clean catch mid-stream urine sample were collected and processed for identification of uropathogens through culture using standard microbiological procedure. Antibiotic susceptibility test was carried out using Kirby Bauer Disk Diffusion method.
Result: The prevalence of UTI in diabetic patients is 15.35% which is greater compared to 12.28% in non-diabetic patients. E.coli was found to be most predominant organism in both diabetic and non-diabetic patients. The most frequently isolated organism in case of diabetic were E.coli (51.42%), K.pneumonie (17.14%), MRSA (8.57%), Pseudomonas aeruginosa (5.71%), MSSA (2.85%), Citrobacter species(2.85%), CONS (2.85%), Candida (2.85%) and two samples showed mixed flora. In case of non-diabetic patients, organisms isolated were E.coli (50%), K.pneumonie(14.28%), MRSA (10.71%), Pseudomonas aeruginosa (10.71%), MSSA (3.57%), Citrobacter species(3.57%), CONS (3.57%) respectively. E.coli isolates from UTI of diabetic patients showed significantly higher resistance rates to CIP, CTX, CAZ, GEN, NIT compared with those from non-diabetic patients. The overall multidrug resistance was observed in 32 out of 35 bacterial isolates in diabetic patients (91.4%).
Conclusion: Prevalence of UTI among diabetic and non-diabetic pts is comparable with published articles. Because of great proportion of asymptomatic bacteruria in diabetic pts, urine culture should be performed in all diabetic pts. Most common uropathogen is E.coli.
Keywords: Diabetes, non-diabetic, Urinary tract infections, Antibiotics, Uropathogens.