IP International Journal of Medical Microbiology and Tropical Diseases


Clinical and epidemiological profile of melioidosis in a tertiary care teaching hospital from South India


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Article Type : Research Article

Author Details: Rosmi Jose*,Chithra Valsan,Sathiavathy K A

Volume : 5

Issue : 2

Online ISSN : 2581-4761

Print ISSN : 2581-4753

Article First Page : 107

Article End Page : 111


Abstract

Melioidosis, which is mainly prevalent in Thailand and Australia, has shown an increasing trend in India in the last few years.
Aim: of this study was to evaluate clinical profile of melioidosis cases in South Indian state Kerala.
Materials and Methods: We retrospectively studied 37 culture proven cases of melioidosis admitted in a tertiary care teaching hospital in South India during January 2013 to December 2017. Demographic data, predisposing factors, clinical presentations, complications, management and outcome were noted and analysed.
Results: There was male preponderance (67.5%) in the study group and the mean age of study group was 43 years and majority of the patients were between the age group of 40-60 years. There was clustering of cases during the rainy season. Diabetes mellitus was present in 67.5% of the cases. Fever was present in 56.7% of cases. Skin and soft tissue (32.4%) involvement was the most common presentation followed by pulmonary melioidosis (29.7%). There were 40.5% of bacteremic melioidosis. Overall mortality was 24.3% and it was 40% among bacteremic cases and 13.6% among non bacteremic melioidosis.
Conclusion: Melioidosis is not uncommon in this part of the country. Clinical profile of Melioidosis cases here are not exactly same as that of other endemic areas of the world. Bacteremic melioidosis has a poorer prognosis than non-bacteremic melioidosis.

Keywords: Melioidosis, Clinical profile, South India.

Doi :-https://doi.org/10.18231/j.ijmmtd.2019.023