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IP International Journal of Medical Paediatrics and Oncology

MRI changes of brain in newborns with hypoxic ischemic encephalopathy clinical stage ii or stage iii- a descriptive study

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Author Details: Jose O, Sheena V

Volume : 3

Issue : 1

Online ISSN : 2581-4702

Print ISSN : 2581-4699

Article First Page : 29

Article End Page : 33


Objectives: The aim of the study was to estimate the proportion of MRI changes in newborns with HIE, to compare the findings of term and preterm babies and to identify if there is any clinical stage specific MRI findings.
Methods: After obtaining clearance from ethical committee, 30 newborns with either stage II or stage III HIE are included in the study. MRI brain was taken between one to two weeks of age once the vitals of the babies are stable & after ensuring euthermia.
Results: Out of the 30 babies, 19 were male babies and 11 female babies. 16 of them were term and 14 of them preterm babies.27 of the total 30 patients had MRI changes of HIE, which accounts for 90%. 17of the 30 mothers were primi mothers which accounts for 56.7%. Most important antenatal factors associated with HIE are gestational hypertension and UTI. Gestational diabetes mellitus and placental/cord factors are also found to be important contributing factors. 33.4% had a history of UTI, 30% gestational hypertension, 23.4% gestational diabetes mellitus in the antenatal period.
Conclusion: Basal ganglia and/or thalamus were affected in 50% of term babies. 87.5% of babies with periventricular leucomalacia are preterms. Intracranial hemorrhage was seen in 7.4% of the babies and all of them were preterms. Out of the four babies with clinical stage III HIE, 50% of them had bilateral basal ganglia involvement. 25% had thalamic involvement. In stage II HIE, no specific change could be found.

HIE; MRI brain; Basal Ganglia Thalami; periventricular leukomalacia