Print ISSN:-2394-546X

Online ISSN:-2394-5478

CODEN : IJMR06

Current Issue

Year 2019

Volume: 6 , Issue: 4

Article view: 564

Article download: 169

Indian Journal of Microbiology Research


MUTATION STUDIES ON STREPTOMYCES FOR AMPHOTERICIN B YIELD IMPROVEMENT


Full Text PDF Share on Facebook Share on Twitter


Author Details : Anitha Upadhyaya, Nagasatya A, Thajuddin N, Paneerselvam A, Upadhyaya Giridhara

Volume : 1, Issue : 1, Year : 2014

Article Page : 56-59


Suggest article by email


Abstract

Four Streptomyces strains isolated from the soil of Western Ghats of India producing Amphotericin B were subjected to random mutagenesis by UV irradiations for yield improvement. The mutants were then screened for their Amphotericin B concentrations and their antifungal activity by agar well diffusion method. Two mutants demonstrated 13% and 16% higher concentration than the isolated strains respectively. Thus mutation can be a very useful tool to minimize production cost with the same benefits.

Keywords: Amphotericin B, UV mutation, Streptomyces, strain improvement

How to cite : Upadhyaya A, Nagasatya A, Thajuddin N, Paneerselvam A, Giridhara U, MUTATION STUDIES ON STREPTOMYCES FOR AMPHOTERICIN B YIELD IMPROVEMENT. Indian J Microbiol Res 2014;1(1):56-59

Copyright © 2014 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)