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Indian Journal of Microbiology Research

Seroprevalence and effect of Hepatitis B and effect on pregnancy at a tertiary care hospital in North Karnataka

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Author Details: Rupali S. Shinde, Aisha M. Parande, B.G. Mantur, Mahantesh V. Parande

Volume : 4

Issue : 3

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 270

Article End Page : 273


Introduction: Hepatitis B virus (HBV) infection is a global public health problem. HBV infected pregnant mothers act as a constant source of infection to the babies. This leads to increased chronic cases of HBV infection despite effective vaccine & antiviral therapy. Thus it becomes very essential to detect such unsuspected otherwise healthy HBV carriers & cases.
Patients and Method: A retrospective study was aimed to study seroprevalence rate of HBV in all pregnant mothers attending the obstetric services from May 2015 to May 2016. All HBsAg positive cases & their babies’ case records were reviewed to study the clinical, demographic data, HBV vaccination & HBV status of the baby.
Results: Prevalence rate is 1.68% in 3800 screened cases. Most cases were from the age group 20-24 years. Primigravids & multigravids were equally infected. Out of 14 delivered cases in the hospital, 13 had live babies & only 1 had IUD. 11 delivered by normal labour whereas only 3 delivered by caesarean section. 3 babies had low birth weight (<2.5kg) whereas 10 babies had birth weight more than 2.5kg. All the babies were fully vaccinated. Only 2 babies’ cases records were available for HBsAg testing & were found negative at 1year of age.
Conclusion: Screening of HBV infection in pregnant females can help clinicians to prevent the infection transmission to the babies by taking appropriate measures. Prevalence rate is low in our study but still screening is highly recommended to reduce the addition of chronic cases annually.

HBV infection, Antenatal cases, HBV vaccination