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Indian Journal of Microbiology Research

Sero prevalence of Hepatitis B surface antigen in patients attending a tertiary care hospital

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Author Details: Lakshmi K., Chitralekha S., Sharanya K., Aishwarya J.R.

Volume : 4

Issue : 3

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 279

Article End Page : 282


Introduction: Hepatitis B virus (HBV) infection is one of the global health problems which can lead to complications like chronic hepatitis and carcinoma of liver. HBV is an emerging threat to the treating clinicians due to the risk of transmission of the virus, increased mortality rate and disease progression to fatal complications.
Aim: The aim of the present study is to determine the baseline prevalence of Hepatitis B surface antigen in patients attending a tertiary care hospital.
Materials and Method: A total of 8190 patients were included in the present study. Screening of HBsAg was done by rapid card test. Positive cases were further confirmed by both Enzyme linked Immunosorbant Assay (ELISA) and Enzyme linked fluorescent assay (ELFA) methods.
Results: Out of 8190 cases, 0.86% of the cases were diagnosed to be positive for HBsAg. Among the positive cases, 0.92% were males and 0.76% were female patients. The seropositivity was higher in the age group of 40-60 years.
Conclusion: The Seroprevalence of hepatitis B surface antigen is more in age group of 40 – 60 years with a male preponderance and is comparatively similar to the previous studies. This indicates the importance of need for strengthening the hepatitis B vaccination in the population, with a high coverage.

: Hepatitis B virus, Hepatitis B surface antigen, Seroprevalence