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Indian Journal of Microbiology Research

Aerobic bacterial profile of blood stream infections and its antimicrobial sensitivity pattern in tertiary care hospital

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Author Details: Mamta Sarwariya, Kalpana Sadawarte, Atul R. Rukadikar, Tukaram Prabhu

Volume : 4

Issue : 4

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 363

Article End Page : 366


Introduction: Blood stream infections cause significant disease and death worldwide and are among the most common healthcare associated infections. Large numbers of cases of treatment failure are being reported due to emergence of drug resistance. Early microbiological diagnosis and determination of antimicrobial sensitivity pattern have been shown to improve treatment outcome.
The present study was aimed to determine the bacterial and antimicrobial sensitivity pattern of blood stream infections in a major tertiary care hospital.
Materials and Method: Prospective cross sectional study was carried out in the Department of Microbiology, People’s College of Medical College and Research Centre, Bhopal from July 2015 to March 2016. Non repetitive blood samples of 647 clinically suspected patients of blood stream infection were collected and processed by standard methods. Isolation and identification of organisms was done as per standard guidelines.
Results: Out of 647 blood culture samples, 106 (16.38%) were positive. The present study showed a predominance of Gram negative bacteremia (55.66%) over Gram positive bacteremia (44.34%).
Conclusion: Appropriate treatment of blood stream infections should be based on the current knowledge of bacterial resistance pattern as provided by microbiology laboratory. This type of study will help in formulating management guidelines and antibiotic policy for effective management and proper antibiotic therapy in patients with bacteremia.

Blood stream Infections, Bacterial Profile, Antimicrobial Sensitivity Testing