Indian Journal of Microbiology Research


Antibiotic Susceptibility Pattern of Escherichia coli Isolated from Urinary Tract Infections and Commensal Escherichia coli from Gastrointestinal Tract of Apparently Healthy Adult - A comparative stud


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Author Details: Divakara SV, Irfan, Meera Meundi

Volume : 4

Issue : 4

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 408

Article End Page : 411


Abstract

Introduction: This study has been under taken to find out the drug resistance patterns exhibited by Escherichia coli (E. coli) originating Urinary Tract Infection (UTI) in comparison to intestinal commensal E.coli.
Materials and Method: One hundred UTI patients who had E. coli isolates were selected for this study. A whole of 100 isolates of E. coli from stool samples of apparently healthy individuals were included as controls. Antibiotic susceptibility testing (AST) was carried out by Kirby Bauer disk diffusion method on Mueller Hinton agar (Hi media).
Result: In the present study E. coli showed more resistance to commonly used antibiotics such as ciprofloxacin, norfloxacin, cefotaxime, ceftriaxone. There is also increasing resistance to gentamicin. In comparison, the antibiotic resistance between cases and controls showed a small difference.
Conclusion: E. coli is the most common cause of UTI, and microscopic examination of the urine is an important screening method for UTI cases. High resistance to widely used antibiotics for treatment may be attributed to inadvertent and indiscriminate use.

Keywords:
Escherichia coli, Urinary Tract Infection, antimicrobial susceptibility testing, antibiotic resistance, commensal E. coli