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Indian Journal of Microbiology Research


A retrospective study comprising analysis of CD4 Cell count among HIV infected patients in tertiary care hospital in western India


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Author Details: Raval Payal N, Purav G. Patel

Volume : 4

Issue : 4

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 431

Article End Page : 433


Abstract

Introduction: HIV is one of the prevalent infectious disease and major threat to community. As the infection progresses, CD4 count hence, immunity decreases with time. CD4 count plays vital role in prognosis of HIV infection.
Materials and Method: CD4 count reports of total of 109 HIV patients who registered and completed 6 months ART treatment during year 2016 were analyzed in this retrospective study. CD4 cell count was done using Flow Cytometry, FACS count (BD Diagnostic).
Results: Baseline CD4 counts at diagnosis of infection for study group was 190.11 cell/cmm. Among them Male were having baseline value of 182.09 cells/cmm and female were having baseline value of 206.36 cells/cmm. After the initiation of ART there is consistent rise in CD4 count among study group patients.
Conclusion: As the baseline CD4 count is low, patients in high risk group should be encouraged to visit ICTC centre for early detection of HIV. CD4 is mainstay among prognostic marker of HIV infection in India. Also steady intake of ART by HIV patients results in rise in CD4 count, increase in immunity and lowering of viral load.

Keywords:
HIV, ART, CD4