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Indian Journal of Microbiology Research

Seroprevalence of transfusion transmissible infections among blood donors at tertiary care hospital in southern Telangana- A 3 year cross sectional study

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Author Details: Dhanashree P Inamdar*,B Anuradha

Volume : 5

Issue : 4

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 446

Article End Page : 450


Introduction: Transfusion of blood and blood products is lifesaving in clinical situations but sometimes it is also a potential source of infection to patients who receive it. Screening for TTIs (Transfusion Transmissible Infections) have a significant role in in preventing morbidity and mortality of patients receiving blood from blood banks.
Aims and Objective: To determine seroprevalence of transfusion transmissible infections among blood group donors in Khammam district of Telangana.
Materials and Methods: A Retrospective cross sectional study was carried out on all donors in blood bank of a tertiary care hospital at Mamata Medical college, Khammam for three years. Screening tests for HIV (Human Immunodeficiency Virus), HBV (Hepatitis B Virus), HCV (Hepatitis C Virus), Malaria and Syphilis included Rapid and ELISA test kits.
Results: Among 5757 donors, 5674 (98.5%) were male and 93(1.5%) were female donors. Overall seroprevalence in a 3 years study showed positivity of 0.42% in HBV, 0.01% in HCV, 0.07% in HIV. More of younger age group donors of 20-25 years were seropositive in HIV, whereas for HBV it was 26-30 years age group. O+ve was the commonest blood group observed showing seropositivity in all three. None of the patients were positive for syphilis or malaria in 3 years study period.
Conclusion: We conclude that seroprevalence of HBV was significantly higher than other infections in our area. Seropositivity for Syphilis and Malaria was not seen in our area.

Keywords: Transfusion transmissible infections (TTI), Seroprevalence, HIV, HBV, HCV.

Doi :-https://doi.org/10.18231/2394-5478.2018.0092