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Indian Journal of Microbiology Research

Preliminary Screening for Prevalence of Hepatitis B, C Viruses and their co-infection: A Hospital Based Study of North India

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Author Details: Mahajan S., Chauhan M., Manish S, Abrol R K.

Volume : 2

Issue : 3

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 189

Article End Page : 191


Background: Viral hepatitis is a cause of considerable morbidity and mortality in human population worldwide due to acute infection and chronic sequelae. The high risk of chronicity of these blood borne infection and its association with hepatocellular carcinoma underscores its public health importance.

Aim: The present study is to determine the prevalence of HBV&HCV infection and their co-infection in patients attending our tertiary care hospital and screened for viral markers in the department of microbiology.
Material and Method: A screening study of one year duration was done in the department of microbiology at Dr RPGMC Tanda (Kangra) H.P. Total 5032 samples for HBV and 2208 samples for HCV infection were considered for the study. Serum sample were analysed for HBsAg as well as for antibodies to HCV using commercially available kits(HEPA SCAN) and(SD-BIOLINE HCV).
Results: 1.41% patients were found to be positive for HBsAg and 1.49% patients were found positive for HCV infection. There was co-infection in 6 patients only. HBV was found more in males as compared to HCV infection which was more in females Age wise prevalence was found maximum in age group between15-60 years. No case was found positive below 5 years of age in our study.
Conclusion: Prevalence of HBV and HCV was below2% showing low endemicity inpopulation included in the study. HCV infection was found more in females in adult group. Co-infection was also found more in females.
Keywords: Acute viral hepatitis, Serum hepatitis, Prevalence, Screening.