IP Indian Journal of Neurosciences


Insular glioma: Ten year experience from a tertiary care center


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Author Details: Prakash Mahantshetti,Raghavendra Nayak*,Bhagwati Salgotra,Dhruv N. Patel,Pavan Kumar Tungala

Volume : 5

Issue : 1

Online ISSN : 2581-916X

Print ISSN : 2581-8236

Article First Page : 5

Article End Page : 11


Abstract

Introduction: We have undertaken this study to find the clinical, radiological, pathological and surgical outcome of patients with insular gliomas operated in our institute over an 11year period.
Material and Methods: Surgical outcome of the conservative safe resection is similar compared to the gross total resection is the hypothesis of the study. So, retrospective analysis of cases of insular glioma treated in a tertiary care institute from 2001 to 2011 was done.
Results: There were 65 male (67.7%) and 31 female patients (total 96 patients) with male: female ratio of 2.1: 1. The median age at diagnosis 36 years. The most common presentation was seizures seen in 70 patients (72.9%), followed by headache. Of the 96 cases 52(54.2%) were on the right and 44(45.8%) on left. Majority of our patients in this study underwent conservative resections with only 7 undergoing >80% resection and 89 underwent <80>80% resection was 18.8 months mean survival and for those < 80>
Conclusion: Insular gliomas are a unique group of gliomas in terms of its location and spread to surrounding lobes. In contrast to most studies, insular gliomas were of high grade in our study. Conservative resection to relieve mass effect, followed by adjuvant therapy is a safe and effective treatment for these critically located gliomas.

Keywords: Insula, Glioma, Seizures.