IP Indian Journal of Neurosciences

Extramedullary fronto-Orbital plasmacytoma- A rare tumour

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Author Details: Kunal N Dholakiya,Tushar V Soni*

Volume : 5

Issue : 1

Online ISSN : 2581-916X

Print ISSN : 2581-8236

Article First Page : 32

Article End Page : 34


Purpose: To report a case of Extramedullary Fronto- orbital plasmacytoma.
Materials and Methods: A 55 year old female presented with swelling in left supraorbital region and ptosis of left eyelid. Mass was smooth, non-tender, non-pulsatile, non-compressible and approximately 3x4 cm in size. Visual acuity was counting fingers. Total excision of tumour was made.
Results: CT scan of brain revealed well defined hyper dense lesion with intense post contrast enhancement in left frontal region causing underlying destruction of left frontal bone, roof of left orbit, and left sphenoid bone, A biopsy was performed revealing that the tumour was composed of plasma cells positive with immunohistochemical stains and epithelial membrane antigen. The diagnosis of extramedullary fronto-orbital plasmacytoma was made.
Conclusion: Extramedullary Plasmacytoma a rare tumour is usually treated by total surgical excision or surgery combined with local radiotherapy and regular long-term follow-ups because disease has high potential to transform into multiple myeloma.

Keywords: Extramedullary Plasmacytoma, Multiple Myeloma, Plasma cells.