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Indian Journal of Obstetrics and Gynecology Research


Bacterial Vaginosis in Pregnancy (<28 Weeks) and its effect on pregnancy outcome: A Study from a western up city


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Author Details: Abhilasha Gupta, Shakun Singh, Rachna Chaudhary, Shipra Nigam

Volume : 3

Issue : 2

Online ISSN : 2394-2754

Print ISSN : 2394-2746

Article First Page : 90

Article End Page : 94


Abstract

Introduction: Bacterial vagiriosis (BV) is an extremely prevalent vaginal condition. BV prevalence in pregnancy is 15-30 percent. BV is a polymicrobial, superficial vaginal infection involving a reduction in the amount of hydrogen-peroxide-producing Lactobacillus and an overgrowth of anaerobic and Gram-negative or Gram-variable bacteria. BV can be symptomatic or asymptomatic. BV in pregnancy has been associated with preterm labour and delivery, premature rupture of membranes amniotic fluid infections and post-partum endometritis.
Materials and Methods: 500 antenatal women of less than 28 are gestation without known risk for PTL admitted or attending antenatal outpatient clinic in Department of Obstetrics and Gynaecology, LLRM and associated SVBP Hospital in last one year were enrolled after a written and informed consent. We studied the presence of bacterial vaginosis in these women uses NUGENTS criteria and correlated it with adverse pregnancy outcome. Prematurity, PROM and post-partum endometritis were considered as adverse pregnancy outcomes.
Result: BV was found in 98 of the 500 women studied. Out of the 98 positive cases, 53 cases were less than 20 weeks gestation and the remaining 45 were between 20-28 weeks gestation. Twenty three of the 98 BV patients had preterm delivery and this association was significant (p<0.0001). Out of the 53 patients of BV diagnosed in 11-20 weeks period of gestation, 12 patients had preterm delivery. The remaining 11 preterm deliveries occurred in BV patients diagnosed after 20 weeks gestation. The association of more number of preterm deliveries in patients with BV diagnosed in 11-20 weeks period of gestation was not significant (p=0.2). Fourteen patients of BV had PROM and this association was also significant (p<0.001). Six patients of BV also had postpartum endometritis.
Conclusion: The above results suggest that screening for BV should start in early pregnancy and a high index of suspicion for preterm delivery should be kept in antenatal patients with BV.

Key Words:
Preterm delivery, Bacterial Vaginosis, Bacterial Vaginosis in pregnancy, Prematurity, Premature rupture of membranes