Indian Journal of Obstetrics and Gynecology Research

A clinical study of the fetal outcome of jaundice in pregnancy in a tertiary care centre

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Author Details: Sunanda KM, Srinivas Krishna Jois, Sukanya Suresh

Volume : 4

Issue : 3

Online ISSN : 2394-2754

Print ISSN : 2394-2746

Article First Page : 230

Article End Page : 234


Introduction: The maternal outcome and other pregnancy outcomes are strongly influenced by the abnormalities of liver function. This study was undertaken to look at the fetal and perinatal outcome in pregnancy with jaundice irrespective of the cause for jaundice.
Materials and Method: The study was done in the department of OBG, Bangalore medical College and research institute over a period of 18 months. All pregnant women with jaundice irrespective of their gestational age were subjected to haematological tests and liver function tests and USG examination and the aetiological diagnosis was established in all the cases. The women were followed during their antenatal, intranatal and postnatal period and the fetal/perinatal outcome were documented and the likely factors influencing the outcome were studied.
Results: There were 31 patients with jaundice putting the incidence to be 0.15%. 13% of the patients were in second trimester and 39% were term pregnancy patients. 35% of them had viral hepatitis, 32% had HELLP syndrome and 22% had intrahepatic cholestasis as the aetiology of jaundice. 92% delivered vaginally and 29% delivered as preterm. More than 45% of the deliveries were associated with adverse fetal outcome – intrauterine fetal demise, still birth etc., 45% had MSAF, 61% required NICU admission, 25.8% babies died.
Conclusion: Jaundice continues to be a problem both for the pregnant woman and continues to have adverse effects on the perinatal outcome and the aetiology of jaundice could be the most important single determining factor for perinatal outcome.

: Jaundice in pregnancy, perinatal outcome in jaundice, Acute fatty liver, Intrahepatic cholestasis