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IP International Journal of Ocular Oncology and Oculoplasty

Immunoglobulin G4(IgG4)-Related Orbital Disease – An overview

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Author Details: Abin Holla, Upender Wali, Abdullah Al-Mujaini

Volume : 3

Issue : 3

Online ISSN : 2581-5016

Print ISSN : 2581-5024

Article First Page : 174

Article End Page : 176


Immunoglobulin G4 related orbital disease is a systemic fibro-inflammatory disorders with a generalized form of clinical manifestations. Although it has a wide spectrum of various pathologies that may affect distant organs as well, there is no single clinical or pathological feature which can be diagnostic. Careful clinicopathological correlation is probably the mainstay of early diagnosis which is so important in preventing severe organ damage. Steroid is effective in managing these cases, but for those patients who are steroid resistant or dependent rituximab appears to be very efficient.