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International Journal of Pharmaceutical Chemistry and Analysis

Burn wound healing potentials of Cynodon dactylon (L.) Pers.

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Author Details: Anand Kumar,Anil K. Sahu,Pankaj Kashyap,Saraswati P. Mishra,Koushlesh Mishra*

Volume : 5

Issue : 3

Online ISSN : 2394-2797

Print ISSN : 2394-2789

Article First Page : 130

Article End Page : 132


In this study the hydro-alcoholic extract of the plant Cynodon dactylon (L.) Pers. was undertaken to evaluate the wound healing property on Burn Wound Model and to compare the effect of the combination of hydro-alcoholic extract of Cynodon dactylon (L.) Pers. and Silver Sulphadiazine with Silver Sulphadiazine alone. Six groups are made and each group consist of 6 animals in it. Each animal of all the six group is inflicted with partial thickness burn wound. The group is numbered as Group I to Group VI. The animals in Group I are taken as control where no drug is given to them. To the Group II animals’ Standard silver sulphasalazine is given. In case of group III animals, they are subjected to hydro-alcoholic extract of Cynodon dactylon. Animals in Group IV and Group V received pure ethanolic extract and aqueous extract respectively. In case of Group VI animal they are treated with standard drug as well as extract. The study mainly focuses on observing parameters like period of epithelialization and the wound contraction percentage. It is observed that the animals in the group which received both hydro alcoholic extract and sulphadiazine showed an improved burn wound contraction. In addition to it the group IV and V shows a decreased epithelialization period.

Keywords: Cynodon dactylon (L.) Pers., Epithelialization, hydro-alcoholic extract (HAE), Silver Sulphadiazine, Wound contraction.

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