International Journal of Pharmaceutical Chemistry and Analysis


Analytical techniques for Pirfenidone and Terizidone: A review


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Article Type : Review Article

Author Details: Atul A. Shirkhedkar,Mohammad Mujeeb G Khan*,Prashant Chaudhari,Pritam I. Pawara

Volume : 6

Issue : 1

Online ISSN : 2394-2797

Print ISSN : 2394-2789

Article First Page : 1

Article End Page : 5


Abstract

Pirfenidone is a broad-spectrum antifibrotic medicine. In 2014, it was approved for the treatment of the idiopathic pulmonary fibrosis (IPF) by the U.S. Food and Drug Administration. Terizidone is WHO categorized group IV anti TB drug. It is an antibiotic effective against Mycobacterium tuberculosis and also M. avium for the treatment of tuberculosis, both pulmonary and extra pulmonary. The fundamental aim of this article to assemble all reported analytical methods for qualitative and quantitative analysis of Pirfenidone and Terizidone in pharmaceutical formulation as well as in biological fluids. It consist of Spectroscopy, high performance liquid chromatography, High performance thin layer chromatography.

Keywords: Pirfenidone, Terizidone, Antifibrotic, Idiopathic pulmonary fibrosis, Analytical method.

Doi :-https://doi.org/10.18231/j.ijpca.2019.001