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Indian Journal of Pathology and Oncology


Rare tumors of retroperitoneum-A diagnostic challenge


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Research Article

Author Details : Ranuva Vaishnavi, Bandavat Sankar Naik, P Premalatha, Ch Ramya, I V Renuka*

Volume : 6, Issue : 4, Year : 2019

Article Page : 671-676


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Abstract

Introduction: Retroperitoneum can show a wide spectrum of diseases, including a variety of rare
benign and malignant neoplasms that can be either primary or metastatic. Most retroperitoneal tumors
are malignant, and soft tissue sarcomas account for one third of the cases. The most common
sarcomas occurring in the retroperitoneum are Liposarcomas, Malignant Fibrous Histiocytomas, and
Leiomyosarcomas. Subtyping of these tumors is important for the different targeted therapeutic options
available.
Aims and Objectives: To study the distribution of benign and malignant retroperitoneal tumors.
Materials and Methods: Study design – Prospective study done in the department of Pathology from
January 2013 to December 2017. Immunohistochemistry (IHC) was done wherever necessary.
Results: A total of 62 retroperitoneal tumours were studied of which 19 were benign & 43 were
malignant. Rare benign tumors encountered were Adrenal Myelolipoma, Benign Fibrous Histiocytoma,
Fibrolipomatous Hamartoma and multiple Paragangliomas. Rare malignant tumors were adult onset
Wilms’ tumor, De-differentiated Liposarcoma, Epithelioid GIST, malignant GIST of the mesentery and
Carcinosarcoma of Kidney.
Conclusion: Amongst the retroperitoneal tumors received, malignant tumors were higher in distribution
than benign tumors. The commonest epithelial tumor being Renal Cell Carcinoma and mesenchymal tumor
being Liposarcoma. The study of rare malignant tumors was done with the help of IHC markers.

Keywords: Retroperitoneum, Sarcoma, Immunohistochemistry, Epithelial, Mesenchymal, Rare tumors.

Doi : 10.18231/j.ijpo.2019.127

How to cite : Vaishnavi R, Naik B S, Premalatha P, Ramya C, Renuka I V, Rare tumors of retroperitoneum-A diagnostic challenge. Indian J Pathol Oncol 2019;6(4):671-676

Copyright © 2019 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)