Indian Journal of Pathology and Oncology


Evaluation of platelet count as a predictive parameter in pediatric patients with dengue fever in a tertiary care center in Davangere


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Author Details: Shwetha JH, Ashoka A, Shashikala P

Volume : 4

Issue : 1

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 77

Article End Page : 79


Abstract

Background: Dengue hemorrhagic fever (DHF) and Dengue Shock Syndrome (DSS) are the two most severe complications of DF and are associated with severe thrombocytopenia and increased vascular permeability.
Objective: To determine the relationship between the platelet count and the severity of the dengue fever among paediatric age group.
Materials and Methods: This prospective study was conducted for 1year among all Serological confirmed dengue patients admitted at a tertiary care center in Davangere. Platelet count was repeated regularly during the hospital stay and also at the time of discharge. Data was entered in excel sheet and results were analysed using epi-data software.
Results: Total 336 were confirmed cases of Dengue. Of these seropositive cases 78.6% had thrombocytopenia (<1L), 32% of the cases were noted in the age group of 6-10years, 50% had platelet counts between 51,000 and 1 lakh. Majority (55.1%) of the cases with severe thrombocytopenia presented with DHF/DSS, the difference of which was found to be statistically significant.
Conclusion: Majority of patients with thrombocytopenia were 6-10 years of age. The occurrence of DHF/DSS increased with the severity of thrombocytopenia.

Keywords:
Dengue, Platelet count, Paediatric age, Thrombocytopenia