Indian Journal of Pathology and Oncology

Study of effect of exchange transfusion in pre-term and term infants: A prospective study

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Author Details: Alaka Sahu, Deepak Kumar Dasmohapatra, Kailash Chandra Agrawal

Volume : 5

Issue : 3

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 494

Article End Page : 497


Hyperbilirubinemia is usually benign in preterm and term infants. Dangerous hyperbilirubinemia is uncommon but may cause long term neurological impairment. In a resource limited rural setup exchange transfusion is an easy, cheap and convenient way for treatment. Our Study focus to improve the outcome in neonatal Hyperbilirubinemia patients in a rural referral center of Odisha.
Aim: Our present study aims at determining the alternations of various haematological and biochemical parameters after exchange transfusion along with adverse outcomes in pre-term and term infants.
Materials and Methods: Total 106 new-borns blood samples were taken from those who have under gone exchange transfusion for different indications. New-borns are divided into two groups pre-term and term infants.
Results: A significant decrease in serum bilirubin values was observed in both the groups after exchange transfusion. Also a significant decrease in blood platelet and increase in calcium level were also present.
Conclusion: Proper approach and prompt management is needed in case of neonatal-hyperbilirubinemia in a resource limited rural setup.

Keywords: Exchange Transfusion, Hyperbilirubinemia.

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