Indian Journal of Pathology and Oncology

Study of lipid profile in patients with stroke

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Article Type : Research Article

Author Details: Mahesh Kumar CH*,Gayatri M,Arun Maski

Volume : 6

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 242

Article End Page : 247


Introduction: Stroke is a global health problem. It is the leading cause of disability and the second leading cause of mortality worldwide. Dyslipidemia is been considered to be a risk factor for stroke, Present study is intended to know association of serum lipid profile with stroke.
Objectives: To determine the prevalence of abnormal lipid profile including extended lipid profile in patients with stroke.
Results: A total of 200 patients with stroke were studied. Among the studied patients 112 (56%) were males and 88 (44%) were females. Mean age of the study population was 56.98yrs (SD = 13.8). Out of 200, 108 (54%) were having total cholesterol value <200mg>> 200 mg/dl. 86(43%) subjects were having Triglyceride level above 150 mg/dl, whereas 114 (57%) were having less than 150 mg/dl. 129 (64.5%) were having HDL value less than 40mg/dl whereas 71 (35.5%) were having HDL > 40 mg/dl. 106 (53%) were having VLDL value < 30mg>>30 mg/dl. 159 (79.5%) were having LDL values above 100 mg/dl and 41 (20.5%) were having LDL value less than 100mg/dl. 74 (37%) were having Apolipoprotein–A1 value less than 120 mg/dl and 126 (63%) were having value > 120 mg/dl. 126 (63%) were having Apolipoprotein–B value <130>> 130 mg/dl. There was no statistically significant difference among males and females in the study subjects. There was statistically significant positive correlation between Total cholesterol & LDL with Apolipoprotein–B (p < 0>
Conclusion: In the present study dyslipidemia, low Apolipoprotein-A1 and high Apolipoprotein B have been found to be associated with stroke.

Keywords: Total cholesterol, Triglycerides, HDL, LDL, Apolipoprotien A1, Dyslipidemia, Stroke.

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