Indian Journal of Pathology and Oncology


Histopathological spectrum of meningiomas: A retrospective study


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Article Type : Research Article

Author Details: Niranjan J*,Vishnu Priya V,Shivarudrappa A S

Volume : 6

Issue : 2

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 256

Article End Page : 260


Abstract

Aims and Objectives: To study the incidence of meningiomas, their histomorphological variants and WHO grading.
Materials and Methods: It is a retrospective study conducted in the department of Pathology, Vydehi institute of medical sciences and research centre, Bangalore. About 57 cases of meningiomas diagnosed from period between 2015-2018 were reviewed retrospectively.
Observation & Results: Meningiomas were most common in the age group of 41-50yrs (36.84%) followed by 51-60yrs (26.32%). Out of the 57 cases, 36 were female (63.16%) and 21 were male (36.84%). Most common histological subtype was found to be Meningothelial meningioma in 19 cases (33.33%) and least common being Rhabdoid and Anaplastic type (1.75% each). Majority of the cases were found to be intracranial (82.46%) in comparison to the spinal meningiomas (15.79%). One of the cases was found to have extracranial origin (1.75%). About 92.98% tumors belonged to WHO GRADE I whereas WHO GRADE II and WHO GRADE III tumor comprise 3.51% each of total cases.
Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient’s prognosis. Hence a continuous revision of histopathological classification systems is required to improve the diagnostic accuracy.

Keywords: CNS tumors, Meningioma, WHO grading, Anaplastic.

Doi :-https://doi.org/10.18231/j.ijpo.2019.050