Indian Journal of Pathology and Oncology


Histopathological spectrum of upper gastrointestinal endoscopic biopsies


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Article Type : Research Article

Author Details: Keerthana Jonnalagadda,Saritha Karre*,Seshagiri Rao Thungaturthi,V D. Praveen Kumar Gorrela

Volume : 6

Issue : 3

Online ISSN : 2394-6792

Print ISSN : 2394-6784

Article First Page : 422

Article End Page : 427


Abstract

Introduction: Wide spectrum of benign and malignant lesions can arise from upper gastrointestinal tract and most of the times histopathological evaluation of endoscopic biopsies gets us to definitive diagnosis. Henceforth the present study aims at finding out different patterns of endoscopic biopsies from upper GI tract.
Materials and Methods: The present descriptive study is conducted in a tertiary care hospital for a year from Oct 2014 to Sep 2015 and includes 70 endoscopic gastric biopsies. Study population includes both sexes with ages ranging from 20yrs to 80 yrs.
Results: The Upper GI Endoscopy includes 18 Esophageal of which 7 (38.9%) are neoplastic and 11 (61.1%) are non-neoplastic and particularly SCC is noticed in 5 (71.4%), mostly from the middle third of esophagus. Similarly Gastric biopsies showed 25(71.4%) non neoplastic and 10 (28.6%) neoplastic and the commonest presentation being Adenocarcinoma. H Pylori is present in 10 (40%) and absent in 15 (60%) of all gastric lesions and coming to 15 duodenal biopsies, 10 are non-neoplastic (66.7%) and 5(33.3%) are neoplastic and 4 are adenocarcinomas.

Conclusions: Through this study we summarize that the Upper GI Endoscopy and histopathological examination helps in early detection of mucosal lesions, both benign and malignant and particularly the malignant lesions will help in better management and preventing grave prognosis. Chronic gastritis is most frequently noticed in non-neoplastic lesions and are predominantly H pylori negative.

Keywords: Biopsy, Endoscopy, Histopathology, Upper GI lesions.

Doi :-https://doi.org/10.18231/j.ijpo.2019.081