Indian Journal of Pharmacy and Pharmacology


Evaluation of the locomotor and skeletal muscle relaxant activities of ethanolic extracts of Acacia Nilotica Linn. BARK. (Mimosaceae)


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Author Details: P. Chakraborty, NN Bala, S. Das

Volume : 3

Issue : 4

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 206

Article End Page : 209


Abstract

Acacia nilotica Linn. Subsp. indica (Family- Mimosaceae) bark has many activities like anti-plasmodial, molluscidal, anti-fungal, anti-microbial activity. The plant has no CNS depressant action found yet, but having such good number of beneficial action to human being has drawn our interest to study the same. The aim of the present study is to investigate the CNS depressant activity of ethanolic extracts A.nilotica bark on mice. The CNS depressant activity was determined by muscle relaxant property, reduction in spontaneous motility. The investigations had brought out that ethanolic extract of Acacia nilotica bark has significant CNS depressant property.

Keywords:
Acacia nilotica, CNS depressant activity, Muscle-relaxant, Locomotor, Ethanolic extract