Indian Journal of Pharmacy and Pharmacology

Formulation and evaluation of orodispersible tablet containing piroxicam by sublimation method

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Author Details: SC Darade, PB Patil, RS Kalkotwar

Volume : 4

Issue : 2

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 77

Article End Page : 82

Abstract

The most preferred route of administration is oral administration of any dosage form because of its self-medication, exact dose of drug and easily administration but difficulty in swallowing in geriatric patients is one important drawback of this route and mentally disturb patients. To solved this problem disintigration time of oral disintegration tablet is within 30 sec. which is disintegrate in mouth. Piroxicam with camphor as subliming agent combined to form fast dissolving tablet.wet granulation technique is used for preparation of Orodispersible tablets of Piroxicam drug. Camphor was removed from the granules by using vaccum. Then tablet were prepared and expose to vaccum. The tablet formulations were evaluated for Disintegration time, dissolution, hardness, friability, weight variation and thickness.

Keywords: Orodispersible tablet (ODTs), Piroxicam, Subliming agent, Camphor