Indian Journal of Pharmacy and Pharmacology


Analysis of cost variation among various statin preparations available in India


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Article Type : Research Article

Author Details: Padmavathi Vutukuru,Kranti Tekulapally*

Volume : 6

Issue : 1

Online ISSN : 2393-9087

Print ISSN : 2393-9079

Article First Page : 14

Article End Page : 17


Abstract

Introduction: Hyperlipidemias are recognized as one of the major risk factors for the development of Coronary Artery Disease (CAD). Statins are the most potent lipid lowering agents currently available that significantly lower the morbidity and mortality associated with CAD.
Aim: To compare the cost of various statins of different brands by calculating the percentage variation of cost.
Materials and Methods: Prices of different statin preparations per 10 tablets/ capsules in rupees were reviewed from Drug today April-June 2018 issue and www.drugsupdate.com for analysis. Maximum and minimum price difference of the same drug manufactured by different pharmaceutical companies was calculated. Percentage variation was calculated as per the following formula

 Drug formulations manufactured by only one company and those whose price could not be obtained from the sources were excluded from analysis.
Results: Maximum companies are manufacturing single drug atorvastatin 10mg (192) and atorvastatin 5 mg + ezetimibe 10mg (40). Highest percentage variation in cost is found with atorvastatin 5 mg (900%) and in atorvastatin 10mg + amlodipine 5 mg (1488%).
Conclusion: There is wide variation in the cost of various statins available in India, which increases the economic burden on patients. Government of India should take more consumer friendly steps to control the cost of drugs. Physicians should maintain a P-drug list and prescribe low cost and effective drugs to improve compliance to drug therapy and ensure effective treatment of the disease.

Keywords: Statins, Cost variation, Hyperlipidemias.

Doi :-https://doi.org/10.18231/2393-9087.2019.0004