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IP Journal of Urology, Nephrology & Hepatology Science


Frequency and pattern of muco-cutaneous manifestations in patients with chronic kidney disease on hemodialysis


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Author Details: Shail Agarwal,Vikash Khandelia*,Vinit Agarwal,Akshy Kumar,Umashankar Nama

Volume : 1

Issue : 2

Online ISSN : XXXX

Print ISSN : XXXX

Article First Page : 18

Article End Page : 21


Abstract

Introduction: Dermatological changes are frequently seen in patients with chronic kidney disease (CKD). Aim of this study was to evaluate the frequency and pattern of hair, nail and cutaneous problems and number of patients with cutaneous manifestations and complications at the site of A-V fistula among CKD patients.
Material and Methods: It was a cross-sectional, observational study conducted in dermatology and nephrology departments at government medical college Kota, Rajasthan between June 2017 and December 2017. Patients with CKD were examined for the diagnosis of dermatological manifestationsAn experienced dermatologist confirmed the diagnosis and histopathological examination was performed for doubtful cases. Disease characteristics like primary disease causing CKD, duration of CKD, stage of CKD, personal/ family history of structural kidney defects, and duration of hemodialysis were recorded.
Results: A total of 100 patients were included in the study. One or more muco-cutaneous manifestations were seen in 94(94%) patients. Xerosis was the most common skin manifestation observed in 70(70%) patients. The most common nail manifestation was leukonychia, seen in 22(22%) patientsThe most common mucosal manifestations were ulcerative mucositis, observed in 22( 22%) patients. The most frequently observed hair manifestation dry and lustureless hairs seen in 26(26%). Local cutaneous changes at the site of A-V fistula were observed in 57(57%) patients.
Conclusion: In the present study, muco-cutaneous manifestations were common in CKD with E-GFR <15>

Keywords: Chronic kidney disease, Muco-cutaneous manifestation, E-GFR(estimated glomerular filtration rate), Hemodialysis, Xerosis.