IP Journal of Diagnostic Pathology and Oncology


A rare vascular lesion of the breast


Full Text PDF Share on Facebook Share on Twitter


Article Type : Case Report

Author Details: Durga Devi S*,Jayaganesh P

Volume : 4

Issue : 2

Online ISSN : 2581-3706

Print ISSN : 2581-3714

Article First Page : 148

Article End Page : 150


Abstract

Introduction: Breast angiosarcoma is an unusual malignancy accounting for 1% of all soft tissue sarcomas. It occurs in both a primary form and a secondary form that has been associated with a history of irradiated breast tissue. This malignant vascular tumour occurs primarily in young women. Epithelioid angiosarcoma, which is a rare aggressive variant of angiosarcoma, arises in the deep soft tissues of the extremities, thyroid gland, skin, adrenal glands, and bone can also be involved. Adverse prognostic factors include advanced age, increased tumor size, retroperitoneal primary site, and an increased proliferative index (MIB >10%). Immunostaining for factor VIII-related antigen, CD31 and CD34 helps with the diagnosis of angiosarcoma of the breast. The prognosis of breast angiosarcoma is poor.Here we report a rare case of 37 year old female presented with swelling of left breast with rapid growth of the tumour. Trucut biopsywas done at the time of diagnosis and thereafter underwent mastectomy and diagnosed as Angiosarcoma of the breast which was thenconfirmed by CD34 Immunohistochemistry.

Keywords: Epithelioid angiosarcoma, CD 34, Breast malignancy.

Doi :-https://doi.org/10.18231/j.jdpo.2019.030