IP Journal of Diagnostic Pathology and Oncology


Study of haematological disorders detected by bone marrow examination at tertiary care hospital


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Article Type : Research Article

Author Details: Kalpana Baliram Rathod,Neeta Wahane*,Leena Nakate,Deepak Kulkarni

Volume : 4

Issue : 3

Online ISSN : 2581-3706

Print ISSN : 2581-3714

Article First Page : 180

Article End Page : 184


Abstract

Bone marrow aspiration & biopsy examination is often required for diagnosis & management of
haematological disorders which have diverse modes of presentation. Mostly of the haematological
disorders present as anaemia, which are diagnosed by bone marrow aspiration (BMA) and bone marrow
biopsy (BMB). I n the department of pathology, the study was conducted to compare the role of bone
marrow aspirate and trephine biopsy for diagnosing the haematological diseases and indications.
Materials and Methods: To check the role of bone marrow aspiration and biopsy in the diagnosis of
haematological disorders this is the aim of study. In the department of pathology at tertiary care teaching
hospital this study was conducted over a period of 2 years from November 2016 to October 2018. A total
of 572 cases were included in this study.
Results: In the present study, both aspiration and biopsy cases were available are 572 were included.
The age ranged from 6 months to 84 years. The 326(56.99%) were males and 246(43%) were females
with M: F=1.32 :1. Clinical indications for bone-marrow examination, The most common indication
was pancytopenia of 201 cases (35.13%) followed by anaemia 167 cases (29.19%), malignancy 79 cases
(13.81%), Hepatosplenomegaly 48 cases (8.39%), thrombocytopenia 47 cases (8.21%) and fever 30 cases
(5.24 %). Most of the cases had hypercellular bone marrow (53%) followed by normocellular marrow
(32%) and hypocellular marrow (15%).

Keywords: Bone marrow, Biopsy, Examination, Haematological disorders.

Doi :-https://doi.org/10.18231/j.jdpo.2019.038